Connect one to a engine or jet and it will last a long time before the fuel runs out, the fuel bar could be yellow or something. There could be a special type of block that has to be placed in the reactor so it can run. If the plane crashed the engine explodes into a spectacular explosion, maybe even destroying a bridge if it is close. Anyone like?
Radiation? Extraordinarily heavy lead shielding? Weight? Size? This is why nuclear powered planes were dropped in the Cold War. Impractical at BEST.
FAK YES.