The project was a joint venture between Construcciones Aeronáuticas SA (CASA) and Indonesian Aerospace (PT. Dirgantara Indonesia), formerly known as IPTN, which formed Airtech International to manage the programme. The partnership applied only to the Series 10 and Series 100/110, with later versions being developed independently. Over 230 of all versions of CN-235 are in service and have accumulated more than 500,000 flight hours.

Design began in January 1980 with first flight on 11 November 1983. Spanish and Indonesian certification was on 20 June 1986; the first flight of the production aircraft was on 19 August 1986 and CASA's FAA type approval was granted on 3 December 1986. The aircraft entered service on 1 March 1988