You will need a basic understanding of variables and variable setter menu for that.

If talking about activation groups:
you can't
.
If talking about variables:
Remember that if a setter is not active, it will not set the value of its corresponding variable during that frame. This means you can make a setter that changes a variable only in specific conditions.
.
E.g., set myVar2 to 0 during a rising edge of myVar1
myVar2: 0
- activator: rate(myVar1)>0